LSU’S Pennington Biomedical Launches New Study Aimed at Understanding Genes Involved in Common Hormonal Disorder Affecting Women
A new study at LSU’s Pennington Biomedical Research Center is looking to identify genes that increase the likelihood of a woman developing Polycystic Ovary Syndrome (PCOS).
PCOS is a hormonal disorder which prevents many women from getting pregnant. It affects one in 12 women worldwide (15 percent of reproductive age women) and is the most common reason many women have trouble getting pregnant. PCOS can cause irregular menstrual cycles, weight gain and is a risk factor for type 2 diabetes.
Through a Gene Mapping of PCOS study, researchers are examining which specific genes, among women of different races, lead to this disorder. The study is being conducted in collaboration with PCOS physician scientist, Dr. Andrea Dunaif, of the Icahn School of Medicine at Mount Sinai, and M. Geoffrey Hayes, PhD., of Northwestern University.
The Pennington Biomedical portion of the study is focused on African-American women, and the center is seeking 300 women of African-American heritage to participate. Women should be between the ages of 18-40, have been diagnosed with PCOS and not taking any medications. (To volunteer, call 225-763-3000 or visit www.pbrc.edu/healthierLA)
“Mapping the genes that increase the likelihood a woman could develop PCOS could help many families who suffer from this condition, which affects not only fertility but metabolic health as well,” said Leanne Redman, PhD, LPFA Endowed Fellow and associate professor, who is leading Pennington Biomedical’s work on the study.
“We know that PCOS runs in families, so genes play an important role. We also know that the number of women affected differs by ethnic groups,” said Redman. “So by studying the genes of large groups of women from diverse ethnic backgrounds, this research study hopes to identify the specific genes that increase PCOS risk, so we can better understand how the disorder develops. This information could lead to new treatments for PCOS.”