The Southwestern Athletic Conference announced the schedules for all 10 SWAC schools for the upcoming 2021 spring football season. The Southern University Jaguars schedule includes one non-conference open date for each team and conference contests scheduled each week beginning in Week One.
The schedule includes 11 total games, features five home contests, and has three non-conference matchups. Home games in bold.
- Sept. 4 – @ Troy, Troy, Ala.
- Sept. 11 – Miles College, (Pete Richardson Classic) Baton Rouge, La.
- Sept. 18 – McNeese State, Baton Rouge, La.
- Sept. 25 – @ Mississippi Valley, Itta Bena, Miss.
- Oct. 2 – Texas Southern (State Fair Showdown), Arlington, Texas
- Oct. 9 – Open
- Oct. 16 – @ Arkansas Pine Bluff, Pine Bluff, Ark.
- Oct. 23 – Prairie View A&M, (Homecoming), Baton Rouge, La.
- Oct. 30 – @ Alcorn State, Lorman, Miss.
- Nov. 6 – Florida A&M, Baton Rouge, La.
- Nov. 13 – Jackson State, Baton Rouge, La.
- Nov. 21 – Open
- Nov. 28 – Grambling State, (Bayou Classic), New Orleans